Cisplatin and electrolyte abnormalities

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WebNov 1, 2024 · Vaughn E. Dobalian Abstract and Figures Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia,... WebCisplatin is a coordinate metal complex with significant antineoplastic activity and various effects, including acute anc chronic renal insufficiency and renal magnesium wasting. …

Lithium concentrations during cisplatin-based chemotherapy …

WebMagnesium depletion usually results from inadequate intake plus impairment of renal conservation or gastrointestinal absorption. There are numerous causes of clinically significant magnesium deficiency (see table Causes of Hypomagnesemia Causes of Hypomagnesemia ).Hypomagnesemia is common among hospitalized patients and … WebNov 1, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, hypophosphatemia, hypocalcemia and hyponatremia. ray bans store near me

Electrolyte Disorders Induced by Antineoplastic Drugs

WebBichet DG, Anderson RJ, Schrier RW (1993) Renal sodium excretion, edematous disorders, and diuretic use. In: Schrier RW (ed) Renal and electrolyte disorders, 4th edn. Little, Brown and Company, Boston, pp 89–161. Google Scholar Heyman SN, Spokes K, Egorin MJ, Epstein FH (1993) Glycine reduces early parenchymal uptake of cisplatin. WebAug 26, 2024 · Electrolyte disturbances can be caused by infections, medicines, trauma and surgery; poor nutritional intake and malabsorption can also contribute to deficiencies [3] . The exact incidence of electrolyte disturbances in the UK is difficult to define, as individual studies have tended to focus on the occurrence in discrete populations [4,5] . WebApr 12, 2024 · In cancer patients, electrolyte disorders are frequent due to tubular functional abnormalities related to chemotherapeutic drugs, the TLS and the impaired secretion of antidiuretic hormone ... As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced ... ray bans smart sunglasses

Cisplatin-induced nephrotoxicity in childhood cancer: comparison ...

Cisplatin: Package Insert - Drugs.com

http://www.ejmanager.com/mnstemps/93/93-1446132625.pdf#:~:text=The%20most%20common%20electrolyte%20abnormality%20associated%20with%20cisplatin,the%20incidence%20of%20which%20varies%20significantly%20between%20studies. WebJan 17, 2015 · In this research, we focused only on electrolyte abnormalities following cisplatin toxicity, to predict electrolyte abnormalities occurred in dogs treated with cisplatin. The present study was carried out to evaluate renal function of dogs administered with cisplatin 0.75 mg/kg/day for 5 consecutive days with assaying of electrolytes and … ray bans stickerWebBlood test results showing low levels may lead to: irregular heartbeat, confusion, blood pressure changes, nervous system or bone disorders. Blood test results showing high … ray bans store locations

"WebCertain medications may cause an electrolyte imbalance such as: Chemotherapy drugs (cisplatin) Diuretics (furosemide [Lasix] or bumetanide [Bumex]) Antibiotics (amphotericin B) Corticosteroids (hydrocortisone) Symptoms of Electrolyte Imbalance: As described, an electrolyte imbalance may create a number of symptoms. " - Cisplatin and electrolyte abnormalities

Cisplatin and electrolyte abnormalities

Gitelman-like syndrome after cisplatin therapy: a case report …

WebJan 1, 2015 · Similarly, hypomagnesemia exclusive to chemotherapeutic agents like cisplatin, ifosfamide, and cetuximab is only seen in cancer patients. This chapter describes the frequency of the most commonly observed electrolyte disorders in the oncology patient and delves into the unique cancer- or chemotherapy-related etiology of these …

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Webelectrolyte imbalance (hyponatremia, hypochloremic alkalosis, hypokalemia, hypomagnesemia ... (with abnormalities of the fasting and 2-hour postprandial sugar) have been observed, and rarely, precipitation of diabetes mellitus has been reported. ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, WebJun 24, 2024 · Cisplatin-induced nephrotoxicity mainly manifests as kidney tubular injury leading to electrolyte disturbances manifested as hypomagnesemia, hypokalemia, and hypophosphatemia and/or increased serum creatinine (occurring more than 7 days after treatment initiation) and decreased glomerular filtration rate [ 8, 9 ].

WebMay 7, 2024 · For the approximately 30% of patients with SCLC who have limited-stage disease at the time of diagnosis (ie, tumors confined to the hemithorax of origin, the … WebDec 9, 2024 · Electrolyte disorders are very common conditions in cancer patients. They mainly concern changes in serum sodium, potassium, calcium, and magnesium levels. In …

WebSep 18, 2024 · NCBI Bookshelf WebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, …

WebA slight electrolyte imbalance may not cause noticeable changes. When problems occur, you may experience: Confusion and irritability. Diarrhea or constipation. Fatigue. Headaches. Irregular or fast heart rate (arrhythmia). Muscle cramps, muscle spasms or weakness. Nausea and vomiting. Numbness or tingling in limbs, fingers and toes.

Web• Hypomagnesemia and Accompanying Electrolyte Abnormalities: Monitor during treatment and for at least 8 weeks following the completion. Replete electrolytes as necessary. (5.6) ... and Cisplatin . 5.6 Hypomagnesemia and Accompanying Electrolyte Abnormalities . 5.7 Increased Tumor Progression, Increased Mortality, or Lack ... simple plan worst day ever lyricsWebMay 24, 2006 · Conclusion: Cisplatin can cause permanent nephrotoxicity, including Gitelman-like syndrome. This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Publication types Case Reports Review MeSH terms Adult Alkalosis / chemically induced* Antineoplastic Agents / adverse effects* ray bans strapWebJan 1, 2015 · Cisplatin administration is commonly associated with electrolyte imbalance. Careful monitoring of renal function and serum electrolytes is therefore essential in this setting. simple plastics.comWebMay 18, 2024 · Impaired kidney function is a relatively common complication of amphotericin B, as are other kidney manifestations, including urinary potassium wasting and … simple plan worst day everWebOct 19, 2024 · Severe electrolyte abnormalities during cisplatin were associated with having 2–6-month CKD or hypertension (adjusted odds ratio (AdjOR) [95% CI]: 2.65 [1.04–6.74]). Having both AKI and severe electrolyte abnormalities was associated with 2–6-month hypertension (AdjOR [95% CI]: 3.64 [1.05–12.62]). Conclusions ray bans student discountWebFurosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, ... Abnormalities should be corrected or the drug temporarily withdrawn. Other medications may also influence serum electrolytes. ... There is a risk of ototoxic effects if cisplatin and ... simple plan withdrawal rulesWebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … simple plastic bottle robot